THE BEST SIDE OF G150

Completely, our information give evidence to the opportunity of mixing CX-5461 and PARPi for improving upon the therapy of HR-deficient HGSOC. We exhibit that CX-5461 improves the synthetic lethal interaction of PARPi with HRD and clearly exhibit that CX-5461 has a distinct mechanism of motion to PARPi. Importantly, we characterized BRCA-mutated an